APAF has a number of mass spectrometers available for services, including:

ABI/Sciex 4700 Proteomics Analyser - automated MALDI-TOF/TOF

Used for MALDI-TOF (PMF) and MALDI-TOF/TOF (PMF + MS/MS) protein identification services.

Micromass Q-TOF Ultima API - nano-LC/MS/MS with high mass accuracy

Coupled with Waters CapLC system and used for 1D nanoLC ESI MS/MS for protein identification.

Also used for ESI analysis of intact protein masses.

ABI/Sciex QSTAR XL- nano-LC/ MS/MS

Coupled with an Agilent 1100 series nanoLC system with dual pumps (CapLC pump and NanoLC pump) and Used for 1D nanoLC ESI MS/MS and 2D nanoLC ESI MS/MS for protein identifications.

Also used for protein quantitation using iTRAQ technique.

ABI/Sciex 4000 QTRAP – nano-LC/MS/MS System

Coupled with an Eksigent nanoLC-2D System and used for MRM biomarker screen, qunatitation and protein modification analysis.

Also used for phosphopeptide analysis and MRM based workflows including MIDAS.

ABI/Sciex QSTAR Elite – LC MALDI

Equipped with a MALDI ion source and used in association with an ABI/Sciex TEMPO LC-MALDI system. The instruments are used for protein identification, modification and Itraq protein quantitation.

In addition, a number of capillary LC systems from Waters and Agilent are available for off-line sample clean up and fractionation.